Answers:
"they are always out and about" means that they are rarely at home, since they are always out. It does not mean that they are always busy, since one can be busy and still be at home.
a lot of how you use expressions depend on who the audience you are writing for. Sometimes they are not appropriate. If its light fiction, its ok, but it should be more sophisticated for college or scientific classes.
Out and about = Out and about town.
I agree with what you say, I am always being accused of being "out and about" meaning I'm not at home and no-one knows where I am! I think that the way you phrase it depends on where you come from and where you live! I really don't think there is a right or wrong in this!
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